Leptin Concentrations in the Polycystic Ovary Syndrome1
نویسندگان
چکیده
منابع مشابه
Leptin concentrations in the polycystic ovary syndrome.
The polycystic ovary syndrome (PCOS) is characterized by menstrual disturbances, chronic anovulation and hyperandrogenism and is associated with insulin resistance and hyperinsulinemia. Leptin, the product of the ob gene, is an adipocyte-secreted molecule that signals the magnitude of energy stores to the brain and has been recently shown to have important effects on the reproductive axis of ro...
متن کاملSerum leptin concentrations in women with polycystic ovary syndrome.
The role of gonadotropins, androgens, and insulin in the regulation of circulating leptin levels is obscure. In order to clarify the relationships of these parameters we studied serum leptin levels in 19 healthy control subjects and in 35 hyperandrogenic and hyperinsulinemic patients with polycystic ovary syndrome (PCOS). Serum leptin concentrations did not differ significantly between PCOS pat...
متن کاملCirculating leptin concentrations and ovarian function in polycystic ovary syndrome.
OBJECTIVE Polycystic ovary syndrome (PCOS) is characterized by ovarian dysfunction. Although the role of leptin in the control of reproduction is unclear, it may be involved in the control of ovulation. The aim of this cross-sectional study was to determine the relationship between circulating leptin concentrations, and anthropometric, metabolic and endocrine variables as well as to examine a p...
متن کاملComparison of leptin concentrations between infertile women with polycystic ovary syndrome and fertile women
BACKGROUND Some studies propose that changes in leptin concentrations (above or under the normal range) result in infertility. Therefore, we investigated serum and follicular fluid leptin concentrations in infertile women with polycystic ovary syndrome (PCOS). OBJECTIVE To study serum and follicular fluid leptin concentrations in infertile women with PCOS. MATERIALS AND METHODS We conducted...
متن کاملLeptin receptor variant in women with polycystic ovary syndrome.
The polycystic ovary syndrome was diagnosed according to the following criteria: [1] bilateral polycystic ovaries on ultrasonography; [2] oligomenorrhea or amenorrhea, hirsutism, obesity, or chronic anovulation, or any combination of these conditions; [3] hyperandrogenemia (elevated serum levels of testosterone, free testosterone, or androstenedione); [4] elevated serum LH levels; and [5] exclu...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1997
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.82.6.4017